Originally published on mensphysique.com on Sunday, 17 February 2013
For those of you who do not know what 7-Keto is, it is a metabolite of the hormone dehydroepiandrosterone (DHEA), which has gained popularity among those who are interested in battling the aging process. Keto-7 boosts immune function and helps to reduce body fat without the risk of conversion to estrogen and testosterone which characterizes DHEA.
Keto-7 (or 7-Keto) is a brand name for the chemical 3-acetyl-7-oxo-dehydroepiandros-terone which is a metabolite mainly produced in the adrenal glands and skin as well as the brain. Levels of this compound rise in the body until about age 20, then start to drop after age 30, declining by 50% by age 50. When Keto-7 levels drop, body fat and total body weight tend to increase, and immune function drops as well. In addition, since the decline in Keto-7 is more pronounced than that of cortisol, cortisol becomes dominant and further challenges the strength of the immune system. So it certainly makes sense to supplement the body with Keto-7 as we age.
Probably the best features of Keto-7 are that it carries no negative side effects, is rapidly absorbed and does not accumulate in the body over time. It counteracts the effect of circulating glucocorticoids such as cortisol, thereby conferring a protective effect on the body’s immune function. For those of you who are asking how it can enhance your health and performance, consider the fact that Keto-7 is a powerful thermogenic and can cause an appreciable increase in the body’s metabolic rate. The process by which Keto-7 does this is by enhancing the activity of three thermogenic enzymes which stimulate fatty acid oxidation. These enzymes drive liver cells to burn fatty acids for energy, resulting in lowered triglycerides. In addition, Keto-7 causes a surge in thyroid hormone activity which further stimulates fat oxidation. Another encouraging effect of Keto-7 on the body is that it improves the blood cholesterol profile. Though Keto-7 only has a slight effect on decreasing LDL cholesterol, it causes a significant increase in HDL levels, thus shifting the total cholesterol profile. Keto-7 also causes a significant rise in apolipo-protein A-1 which has a protective effect on cardiovascular health.
Many proponents of Keto-7 supplementation suggest combination therapy with both Keto-7 and DHEA. Both of these substances can work in tandem to boost estrogen and testosterone levels to optimum range. DHEA can cause facial hair growth and oily skin in women who take large amounts of DHEA, so the use of Keto-7 with a smaller dose of DHEA can eliminate this problem. DHEA cannot be administered to individuals with prostate cancer or breast cancer, which makes Keto-7 an acceptable alternative.
Make sure to supplement with Keto-7 in the morning when the body’s natural production is at its peak. I take my dose with my first meal in the morning, but you can also take this supplement on an empty stomach. Some proponents advise taking two doses daily, but I believe a 100 mg dose once daily in the morning suffices for most individuals. Avoid taking it in the evening, as it may stimulate brain activity and result in insomnia.
Keto-7 should be taken by anyone who wants to combat the aging process and improve body composition without adversely affecting natural hormonal levels of estrogen and testosterone.