Low Vitamin D Levels Linked to Macular Degeneration Risk

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Vitamin D has gotten more attention in recent years, as a result of extensive research which has explored the impact of a deficiency in this important substance. A meta-analysis on vitamin D deficiency which was published earlier this year in Maturitas revealed a possible correlation between low levels of 25-hydroxyvitamin D in the body and increased risk for development of age-related macular degeneration (AMD). Furthermore, scientists surmise that if a vitamin D deficiency is corrected well before any signs of AMD are present, the disease’s prognosis is much improved.

The meta-analysis revealed that individuals with macular degeneration had vitamin D levels which were an average of 15% lower than levels in individuals without the disease. Another analysis revealed that subjects with highest circulating levels of vitamin had 50-80% lower odds of developing AMD compared with those who had the lowest circulating vitamin D levels.

However, despite all of these findings, it is not yet clear whether vitamin D supplementation would have a protective effect against AMD. In addition, the lower vitamin D levels found in some subjects may have resulted from the pathophysiology of AMD itself.

Rather than take a chance, I would prefer to promote vitamin D supplementation under the assumption that low vitamin D levels are a causative factor in the development of AMD. I also lean strongly towards a brief amount of exposure to sunlight daily in order to boost vitamin D levels naturally. In order for such exposure to be effective, sunscreen cannot be used around the clock. My recommendation is to sit in the sun for 3 minutes daily.

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